“It's in the misery of some unnamed slum that the next killer virus will emerge.”

“I only know what I have seen. What I have not seen doesn't make my heart heavy.”

“And where we are met with cynicism and doubt and fear and those who tell us that we can't, we will respond with that timeless creed that sums up the spirit of the American people in three simple words -yes, we can.”

“They, they, they. That was the problem with people like Joyce. They talked about the richness of their multicultural heritage and it sounded real good, until you noticed that they avoided black people. It wasn't a matter of conscious choice, necessarily, just a matter of gravitational pull, the way integration always worked, a one-way street. The minority assimilated into the dominant culture, not the other way around. Only white culture could be neutral and objective. Only white culture could be nonracial, willing to adopt the occasional exotic into its ranks. Only white culture had individuals. And we, the half-breeds and the college-degreed, take a survey of the situation and think to ourselves, Why should we get lumped in with the losers if we don't want to? We become only so grateful to lose ourselves in the crowd, America's happy, faceless marketplace; and we're never so outraged as when a cabbie drives past us or the woman in the elevator clutches her purse, not so much because we're bothered by the fact that such indignities are what less fortunate coloreds have to put up with every single day of their lives-- although that's what we tell ourselves-- but because we're wearing a Brooks Brothers suit and speak impeccable English and yet have somehow been mistaken for an ordinary nigger. Don't know who I am? I'm an individual!”

“Where there is no experience the wise man is silent.”

“Life doesn't count for much unless you're willing to do your small part to leave our children – all of our children – a better world. Even if it's difficult. Even if the work seems great. Even if we don't get very far in our lifetime.”

“What makes a man is not the ability to have a child but having the courage to raise one.”

“For we know that our patchwork heritage is a strength, not a weakness.”

“Don’t be thick, all right? I’m not just talking about one time. Look, I ask Monica out, she says no. I say okay … your shit’s not so hot anyway.”

“What matters is how well we have loved.”

“I find comfort in the fact that the longer I'm in politics the less nourishing popularity becomes, that striving for power and rank and fame seems to betray a poverty of ambition, and that I am answerable mainly to the steady gaze of my own conscience.”

“At the moment that we persuade a child, any child, to cross that threshold, that magic threshold into a library, we change their lives forever, for the better”

“I can no more disown (Jeremiah Wright) than I can disown the black community. I can no more disown him than I can my white grandmother – a woman who helped raise me, a woman who sacrificed again and again for me, a woman who loves me as much as she loves anything in this world, but a woman who once confessed her fear of black men who passed by her on the street, and who on more than one occasion has uttered racial or ethnic stereotypes that made me cringe.”

“Everybody knows that it makes no sense that you send a kid to the emergency room for a treatable illness like asthma. They end up taking up a hospital bed. It costs when, if you, they just gave, you gave, treatment early, and they got some treatment, and uhhh a breathalyzer, or uhh, an inhalator, not a breathalyzer...”

“No, no. I have been practicing...I bowled a 129. It's like -- it was like Special Olympics, or something." --making an off-hand joke during an appearance on "The Tonight Show", March 19, 2009”