“New York, like London, seems to be a cloacina [toilet] of all the depravities of human nature.”

“I have received the favor of your letter of August 17th, and with it the volume you were so kind as to send me on the Literature of Negroes. Be assured that no person living wishes more sincerely than I do, to see a complete refutation of the doubts I have myself entertained and expressed on the grade of understanding allotted to them by nature, and to find that in this respect they are on a par with ourselves. My doubts were the result of personal observation on the limited sphere of my own State, where the opportunities for the development of their genius were not favorable, and those of exercising it still less so. I expressed them therefore with great hesitation; but whatever be their degree of talent it is no measure of their rights. Because Sir Isaac Newton was superior to others in understanding, he was not therefore lord of the person or property of others. On this subject they are gaining daily in the opinions of nations, and hopeful advances are making towards their reestablishment on an equal footing with the other colors of the human family.”

“While the art of printing is left to us science can never be retrograde; what is once acquired of real knowledge can never be lost.”

“We seem not to perceive that, by the law of nature, one generation is to another as one independent nation is to another.”

“Men have differed in opinion, and been divided into parties by these opinions, from the first origin of societies; and in all governments where they have been permitted freely to think and to speak. the same political parties which now agitate the U.S. have existed through all time. Whether the power of the people, or that of the (best men; nobles) should prevail, were questions which kept the states of Greece and rome in eternal convulsions...” 

“...never [enter] into dispute or argument with another. I never saw an instance of one of two disputants convincing the other by argument. I have seen many, on their getting warm, becoming rude, & shooting one another. ... When I hear another express an opinion which is not mine, I say to myself, he has a right to his opinion, as I to mine; why should I question it? His error does me no injury, and shall I become a Don Quixote, to bring all men by force of argument to one opinion? ... There are two classes of disputants most frequently to be met with among us. The first is of young students, just entered the threshold of science, with a first view of its outlines, not yet filled up with the details & modifications which a further progress would bring to their knoledge. The other consists of the ill-tempered & rude men in society, who have taken up a passion for politics. ... Consider yourself, when with them, as among the patients of Bedlam, needing medical more than moral counsel. Be a listener only, keep within yourself, and endeavor to establish with yourself the habit of silence, especially on politics. In the fevered state of our country, no good can ever result from any attempt to set one of these fiery zealots to rights, either in fact or principle. They are determined as to the facts they will believe, and the opinions on which they will act. Get by them, therefore, as you would by an angry bull; it is not for a man of sense to dispute the road with such an animal.”

“Of all machines, the human heart is the most complicated and inexplicable.”

“Everything yields to diligence”

“Honesty is the first chapter in the book of wisdom.” 

“I like a little rebellion now and then. It is like a storm in the atmosphere.”

“All are dead, and ourselves left alone amidst a new generation whom we know not, and who know us not.”

“So inscrutable is the arrangement of causes and consequences in this world, that a two-penny duty on tea, unjustly imposed in a sequestered part of it, changes the condition of all its inhabitants.”

“Experience declares that man is the only animal which devours his own kind; for I can apply no milder term to the governments of Europe, and to the general prey of the rich on the poor.”

“I'm a greater believer in luck, and I find the harder I work the more I have of it”

“He who permits himself to tell a lie once, finds it much easier to do it the second time.”