“A little patience, and we shall see the reign of witches pass over, their spells dissolve, and the people, recovering their true sight, restore their government to its true principles. It is true that in the meantime we are suffering deeply in spirit, and incurring the horrors of a war and long oppressions of enormous public debt...If the game runs sometime against us at home, we must have patience till luck turns, and then we shall have an opportunity of winning back the principles we have lost, for this is a game where principles are at stake.” 

“While the art of printing is left to us science can never be retrograde; what is once acquired of real knowledge can never be lost.”

“And to preserve their independence, we must not let our rulers load us with perpetual debt. We must make our election between economy and liberty, or profusion and servitude. If we run into such debts, as that we must be taxed in our meat and in our drink, in our necessaries and our comforts, in our labors and our amusements, for our callings and our creeds, as the people of England are, our people, like them, must come to labor sixteen hours in the twenty-four, give the earnings of fifteen of these to the government for their debts and daily expenses; and the sixteenth being insufficient to afford us bread, we must live, as they now do, on oatmeal and potatoes; have no time to think, no means of calling the mismanagers to account; but be glad to obtain subsistence by hiring ourselves to rivet their chains on the necks of our fellow-sufferers.” 

“Reason and free inquiry are the only effectual agents against error.”

“The earth belongs always to the living generations.”

“...never [enter] into dispute or argument with another. I never saw an instance of one of two disputants convincing the other by argument. I have seen many, on their getting warm, becoming rude, & shooting one another. ... When I hear another express an opinion which is not mine, I say to myself, he has a right to his opinion, as I to mine; why should I question it? His error does me no injury, and shall I become a Don Quixote, to bring all men by force of argument to one opinion? ... There are two classes of disputants most frequently to be met with among us. The first is of young students, just entered the threshold of science, with a first view of its outlines, not yet filled up with the details & modifications which a further progress would bring to their knoledge. The other consists of the ill-tempered & rude men in society, who have taken up a passion for politics. ... Consider yourself, when with them, as among the patients of Bedlam, needing medical more than moral counsel. Be a listener only, keep within yourself, and endeavor to establish with yourself the habit of silence, especially on politics. In the fevered state of our country, no good can ever result from any attempt to set one of these fiery zealots to rights, either in fact or principle. They are determined as to the facts they will believe, and the opinions on which they will act. Get by them, therefore, as you would by an angry bull; it is not for a man of sense to dispute the road with such an animal.”

“I am mortified to be told that, in the United States of America, the sale of a book can become a subject of inquiry, and of criminal inquiry too. ”

“I do not take a single newspaper, nor read one a month, and I feel myself infinitely the happier for it.” 

“Peace and friendship with all mankind is our wisest policy, and I wish we may be permitted to pursue it.”

“I hold it that a little rebellion now and then is a good thing, and as necessary in the political world as storms in the physical.” 

“When describing the University of Virginia: Here, We are not afraid to follow truth wherever it may lead, nor to tolerate any error so long as reason is left free to combat it.”

“I set out on this ground, which I suppose to be self-evident, that the dart belongs in usufruct to the living.”

“...We are all Federalists,and we are all Republicans.”

“[A] lawyer without books would be like a workman without tools.”

“Question with boldness even the existence of a God; because, if there be one, he must more approve of the homage of reason, than that of blind-folded fear.”