“I almost shudder at the thought of alluding to the most fatal example of the abuses of grief which the history of mankind has preserved - the Cross. Consider what calamities that engine of grief has produced! With the rational respect that is due to it, knavish priests have added prostitutions of it, that fill or might fill the blackest and bloodiest pages of human history.

“There exists indeed an opposition to it [building of UVA, Jefferson's secular college] by the friends of William and Mary, which is not strong. The most restive is that of the priests of the different religious sects, who dread the advance of science as witches do the approach of day-light; and scowl on it the fatal harbinger announcing the subversion of the duperies on which they live. In this the Presbyterian clergy take the lead. The tocsin is sounded in all their pulpits, and the first alarm denounced is against the particular creed of Doctr. Cooper; and as impudently denounced as if they really knew what it is.

“Follow truth wherever it may lead you.”

“A machine for making revolutions is doing precisely the wrong thing at just the right time.”

“A nation which expects to be ignorant and free, in a state of civilization, expects that which never was and never will be.”

“The most valuable of all talents is that of never using two words when one will do.”

“Where the press is free and every man able to read, all is safe.”

“Do not bite at the bait of pleasure till you know there is no hook beneath it.”

“A morsel of genuine history is a thing so rare as to be always valuable.”

“If there be any among us who would wish to dissolve this Union, or to change its republican form, let them stand undisturbed as monuments of the safety with which error of opinion may be tolerated, where reason is left free to combat it."

“Nobody is better than you and remember, you are better than nobody.

“Altho' I rarely waste time in reading on theological subjects, as mangled by our Pseudo-Christians, yet I can readily suppose Basanistos may be amusing. Ridicule is the only weapon which can be used against unintelligible propositions. Ideas must be distinct before reason can act upon them; and no man ever had a distinct idea of the trinity. It is mere Abracadabra of the mountebanks calling themselves the priests of Jesus. If it could be understood it would not answer their purpose. Their security is in their faculty of shedding darkness, like the scuttlefish, thro' the element in which they move, and making it impenetrable to the eye of a pursuing enemy, and there they will skulk.

“To your request of my opinion of the manner in which a newspaper should be conducted, so as to be most useful, I should answer, ‘by restraining it to true facts & sound principles only.’ Yet I fear such a paper would find few subscribers. It is a melancholy truth, that a suppression of the press could not more compleatly deprive the nation of its benefits, than is done by its abandoned prostitution to falsehood. Nothing can now be believed which is seen in a newspaper. Truth itself becomes suspicious by being put into that polluted vehicle. The real extent of this state of misinformation is known only to those who are in situations to confront facts within their knolege with the lies of the day. I really look with commiseration over the great body of my fellow citizens, who, reading newspapers, live & die in the belief, that they have known something of what has been passing in the world in their time; whereas the accounts they have read in newspapers are just as true a history of any other period of the world as of the present, except that the real names of the day are affixed to their fables. General facts may indeed be collected from them, such as that Europe is now at war, that Bonaparte has been a successful warrior, that he has subjected a great portion of Europe to his will, &c., &c.; but no details can be relied on. I will add, that the man who never looks into a newspaper is better informed than he who reads them; inasmuch as he who knows nothing is nearer to truth than he whose mind is filled with falsehoods & errors. He who reads nothing will still learn the great facts, and the details are all false.” —Letter to John Norvell, 14 June 1807 [Works 10:417--18]” 

“I haven't failed. I've just found 10,000 ways that don't work.”

“The happiest moments of my life have been the few which I have passed at home in the bosom of my family”