“Nobody is better than you and remember, you are better than nobody.

“The opinions of men are not the object of civil government, nor under its jurisdiction.” 

“Our civil rights have no dependence upon our religious opinions more than our opinions in physics or geometry.”

“If it is believed that these elementary schools will be better managed by the governor and council or any other general authority of the government, than by the parents within each ward, it is a belief against all experience.”

“I prefer dangerous freedom over peaceful slavery.”

“When angry, count ten before you speak; if very angry, an hundred.”

“An injured friend is the bitterest of foes.”

“The attempt of Lavoisier to reform chemical nomenclature is premature. One single experiment may destroy the whole filiation of his terms; and his string of sulphates, sulphites, and sulphures, may have served no end than to have retarded the progress of science by a jargon, from the confusion of which time will be requisite to extricate us.” 

“The doctor of the future will give no medicine, but will interest his (sic)patient in the care of the human frame, in diet and in the cause and prevention of disease”

“Whenever you do a thing, act as if all the world were watching.”

“There exists indeed an opposition to it [building of UVA, Jefferson's secular college] by the friends of William and Mary, which is not strong. The most restive is that of the priests of the different religious sects, who dread the advance of science as witches do the approach of day-light; and scowl on it the fatal harbinger announcing the subversion of the duperies on which they live. In this the Presbyterian clergy take the lead. The tocsin is sounded in all their pulpits, and the first alarm denounced is against the particular creed of Doctr. Cooper; and as impudently denounced as if they really knew what it is.

“Nothing can stop the man with the right mental attitude from achieving his goal. Nothing on earth can help the man with the wrong attitude.”

“Some men look at constitutions with sanctimonious reverence, and deem them like the ark of the covenant, too sacred to be touched. They ascribe to the men of the preceding age a wisdom more than human, and suppose what they did to be beyond amendment. I knew that age well; I belonged to it, and labored with it. It deserved well of its country. It was very like the present, but without the experience of the present; and forty years of experience in government is worth a century of book-reading; and this they would say themselves, were they to rise from the dead. I am certainly not an advocate for frequent and untried changes in laws and constitutions. I think moderate imperfections had better be borne with; because, when once known, we accommodate ourselves to them, and find practical means of correcting their ill effects. But I know also, that laws and institutions must go hand in hand with the progress of the human mind. As that becomes more developed, more enlightened, as new discoveries are made, new truths disclosed, and manners and opinions change with the change of circumstances, institutions must advance also, and keep pace with the times. We might as well require a man to wear still the coat which fitted him when a boy, as civilized society to remain ever under the regimen of their barbarous ancestors.” 

“A government big enough to give you everything you want, is strong enough to take everything you have

“The art of life is the art of avoiding pain.”